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1. Identificação
Tipo de ReferênciaArtigo em Revista Científica (Journal Article)
Código do Detentorisadg {BR SPINPE} ibi 8JMKD3MGPCW/3DT298S
Sitemtc-m21d.sid.inpe.br (namespace prefix: upn:44QHRCS)
Identificador8JMKD3MGP3W34T/4BJCQFS
Repositóriosid.inpe.br/mtc-m21d/2024/07.02.15.04   (acesso restrito)
Última Atualização2024:07.02.15.04.45 (UTC) simone
Repositório de Metadadossid.inpe.br/mtc-m21d/2024/07.02.15.04.46
Última Atualização dos Metadados2024:07.06.08.20.05 (UTC) administrator
DOI10.1016/j.jnoncrysol.2024.123059
ISSN0022-3093
Chave de CitaçãoGanemOliPagOkaLop:2024:ApEnIo
TítuloUnlocking the potential of multicomponent mesoporous bioactive glass nanoparticles: An approach to enhanced ion therapy
Ano2024
MêsAug.
Data de Acesso23 out. 2026
Tipo de Trabalhojournal article
Tipo SecundárioPRE PI
Número de Arquivos1
Tamanho18362 KiB
2. Contextualização
Autor1 Ganem, G. C. A.
2 Oliveira, L. F. M.
3 Pagan, B. M.
4 Okamoto, Sayuri
5 Lopes, J. H.
Grupo1
2
3
4 COPDT-CGIP-INPE-MCTI-GOV-BR
Afiliação1 Instituto Tecnológico de Aeronáutica (ITA)
2 Instituto Tecnológico de Aeronáutica (ITA)
3 Instituto Tecnológico de Aeronáutica (ITA)
4 Instituto Nacional de Pesquisas Espaciais (INPE)
5 Instituto Tecnológico de Aeronáutica (ITA)
Endereço de e-Mail do Autor1
2
3
4 sayuri.okamoto@inpe.br
5 lopes@ita.br
RevistaJournal of Non-Crystalline Solids
Volume638
Páginase123059
Nota SecundáriaA1_INTERDISCIPLINAR A1_ENGENHARIAS_III A1_ENGENHARIAS_II B1_MATERIAIS B1_ENGENHARIAS_IV B1_CIÊNCIA_DE_ALIMENTOS B2_QUÍMICA B2_ODONTOLOGIA B2_MEDICINA_II B2_CIÊNCIAS_BIOLÓGICAS_II B2_BIOTECNOLOGIA B2_ASTRONOMIA_/_FÍSICA C_BIODIVERSIDADE
Acervo Hospedeirourlib.net/www/2021/06.04.03.40 upn:44QHRCS
Histórico (UTC)2024-07-02 15:04:46 :: simone -> administrator ::
2024-07-02 15:04:51 :: administrator -> simone :: 2024
2024-07-02 15:05:16 :: simone -> administrator :: 2024
2024-07-06 08:20:05 :: administrator -> simone :: 2024
3. Conteúdo e estrutura
É a matriz ou uma cópia?é a matriz
Estágio do Conteúdoconcluido
Transferível1
Tipo do ConteúdoExternal Contribution
Tipo de Versãopublisher
Palavras-ChaveBorosilicate
Copper
Ion therapy
Mesoporous bioactive glass
Tissue engineering
Zinc
ResumoThis work presents the synthesis and characterization of a multicomponent mesoporous bioactive glass (MMBG) derived from the composition of 58S glass modified with copper, zinc, and boron. Morphological data revealed the presence of spherical particles with an average size of 616 nm and a specific surface area of 295 m2·g−1. X-ray diffractogram analysis confirmed the lack of long-range order in the MMBG, indicating the presence of a disordered vitreous structure characteristic of glass. The structural scenario of the bioactive glass MMBG reveals a characteristic configuration of borosilicate glasses, where the [BO4] polyhedra, along with SiO4 tetrahedra, constitute the backbone of the glassy matrix. Concerning zinc and copper ions, they function similarly to calcium in compensating for the remaining negative charges within the borosilicate network, behaving as typical network-modifying ions. The presence of these heavy ions, coupled with the formation of the borosilicate network in MMBG, led to a 20 % increase in density compared to 58S glass. Additionally, alterations in the chemical composition and structure of MMBG resulted in a reduction in molar volume compared to 58S, indicating a decrease in the volume occupied by one mole of oxygen in the glass matrix, thereby increasing the oxygen packing density. The pH studies reveal that changes in the chemical composition of MMBG did not compromise its chemical reactivity in aqueous environments. The capability of MMBG glass to act as a bioactive agent for ion therapy is evidenced by its ability to deliver Zn and Cu ions, as substantiated by the gradual disappearance of absorption in wavenumber range of 690470 cm−1, attributed to the vibration of Zn-O and Cu-O bonds. Preliminary in vitro assay for bioactivity in SBF revealed that the formation of apatite layer on the surface of MMBG glass was notably thicker and denser compared to 58S glass. This result highlights the superior bioactive response of the MMBG bioactive glass, indicating its potential as an exceptionally favorable material for various biomedical applications.
ÁreaCOMB
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4. Condições de acesso e uso
Idiomaen
Arquivo Alvo1-s2.0-S0022309324002382-main.pdf
Grupo de Usuáriossimone
Grupo de Leitoresadministrator
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Visibilidadeshown
Política de Arquivamentodenypublisher denyfinaldraft24
Permissão de Leituradeny from all and allow from 150.163
Permissão de Atualizaçãonão transferida
5. Fontes relacionadas
Repositório Espelhourlib.net/www/2021/06.04.03.40.25
Unidades Imediatamente Superiores8JMKD3MGPCW/46KUES5
Lista de Itens Citandosid.inpe.br/bibdigital/2022/04.03.23.11 - 75
DivulgaçãoWEBSCI; PORTALCAPES; COMPENDEX.
6. Notas
Campos Vaziosalternatejournal archivist callnumber copyholder copyright creatorhistory descriptionlevel e-mailaddress format isbn label lineage mark nextedition notes number orcid parameterlist parentrepositories previousedition previouslowerunit progress project resumeid rightsholder schedulinginformation secondarydate secondarykey session shorttitle sponsor subject tertiarymark tertiarytype url
7. Controle da descrição
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